Adsorption of proteins on TiO2 particles influences their aggregation and cell penetration

• The gelatin and ?-lactoglobulin are adsorbed on TiO 2 nanoparticles. proteins improve the colloidal stability of prevent salt-induced aggregation enhance penetration inside human intestinal epithelial cells. favored most efficiently nanoparticles cell penetration. known as E171 one controversial food additive due to its potential toxicity. In this work, main hypothesis is that their favor To do so, were coated with reach interfacial concentrations about 0.25 mg/mg 0.32 mg/mg, respectively. measurement NP size showed protein coating FTIR analysis suggests structure modified after adsorption. cells was shown quantify by using confocal Raman microscopy. promoting role demonstrated for both ?-lactoglobulin. Finally, results allow establishing a correlation between ability